At a glance, it becomes very obvious that the Ledger Nano S is the best bet for if you're an altcoin enthusiast.
The Nano S currently supports 26 cryptocurrencies not supported by Trezor or KeepKey.
High market cap coins only supported by the Nano S (and sometimes also the Blue) include Ripple, Stellar, Tron, NEO, VeChain, and Qtum.
If you're interested in securely storing any of the coins that are only supported by the Ledger Nano S, then we'd strongly recommend the Nano S for you.
For those of you who are Bitcoin maximalists or are only interested in coins supported by Trezor devices, this is where things get interesting.
From a user-friendliness standpoint, we favor Trezor's web interface to Ledger's Ledger Live" apps.
While setting up your Trezor device, you'll be prompted to install the "Trezor Bridge".
This is a simple application for your computer that will allow your hardware wallet to communicate with the Trezor web wallet interface. Aside from installing the program, you should never even notice it again, so long as you're using the same computer.
New computers you want to use will also need to install the bridge.
After setting up the bridge, you'll be able to fully interact with the Trezor web wallet interface.
The wallet allows you to seamlessly switch between different supported coin wallets. With the exception of Ethereum, Ethereum Classic, and NEM, you can view your balances, send transactions, and view your addresses for receiving transfers all from this one page.
Ethereum, Ethereum Classic, and NEM are unique in the way they operate.
For these cryptocurrencies, Trezor has been integrated with third-party wallets. This means you get all of the security benefits of Trezor but can't use these coins' wallets directly from Trezor's web interface.
With that said, we still find the Trezor's approach to these altcoins more user-friendly than Ledger's app system (which we'll get to just below).
For example, when you click on "Ethereum (ETH)" in the drop-down menu, you'll see the following pop up to use MyEtherWallet or GoCrypto's Ethereum wallet.
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You can also navigate to these sites directly.
Once at MyEtherWallet, you can select to connect your Trezor device.
After connecting to MyEtherWallet, you can then use your Ethereum addresses to send and receive transactions.
Note that you can also use MyEtherWallet in combination with Trezor to store all ERC-20 tokens.
Ledger devices use "Ledger Live", Ledger apps, and some third-party wallet integrations.
For those who have used the old Ledger app manager, Ledger live is a big step up for changing between wallets. As the name implies, Ledger Live allows you to view your account balances without having your hardware wallet connected, a feature lacking from Trezor.
What we find most annoying about the Ledger system is the fact that you have to open apps from your device.
This means using the hardware every time you want to switch between which wallet apps you're using.
While this might sound like a minor inconvenience, it may become super frustrating over time. It's especially cumbersome if you're used to Trezor's seamless switching between wallets.
This shortcoming mostly affects users of the Nano S, as the Blue's touchscreen makes switching between wallets less of a hassle.
All hardware wallets in this guide require users to enter a PIN code to access their device.
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In a similar vein to the above annoyance, Ledger hardware wallets can be a pain to access. Whereas Trezors have you enter a PIN code on your computer (from an array of numbers shown on the devices), Ledger devices require you to enter your PIN on the hardware itself.
Pin Entry on Ledger Nano S vs Trezor
Again, this is less of an issue for the Ledger Blue, as it's easier to interact with the Blue's touchscreen, compared to the Nano's two button set up.
It's important to note that Ledger's lackluster system is at least partially due to the large number of currencies it supports and its team's dedication to security.
KeepKey uses a simple chrome app for accessing your wallets.
While KeepKey boasts even fewer supported cryptocurrencies than Trezor, it offers a pretty great overall user experience for the coins it does support. Unlike the Nano S, we did not have any major frustrations with the KeepKey.
Price, Value, and Final Thoughts
Ledger Nano S
Despite the Ledger Nano S having some annoyances, it's hard to argue this is not the best hardware wallet available.
At $99.99, the Nano S is the cheapest hardware wallet while simultaneously offering the most supported cryptocurrencies.
For many, the Nano S is a no brainer just based off of these facts.
It's essentially a necessity for altcoin holders, even including popular altcoins like Ripple, Stellar, and Tron.
Even for those who are new to crypto and haven't yet entered into the altcoin waters, you may want to prepare for your seemingly inevitable entry into these markets by opting for the Nano S.
Trezor One & Trezor Model T
The Trezor One (€89 ($106) is a tried and true hardware wallet, with a user experience we find better than the Ledger.
If you don't need the coin support of Ledgers, then we personally would recommend the Trezor One for this reason. If the roughly $6 difference in price is a deal breaker for you, then you might want to hold off on even purchasing a hardware wallet until you have a larger investment to protect.
Now if you're determined to own a touchscreen hardware wallet, the Model T offers one for about $100 cheaper than the Ledger Blue (~$170 vs $269.99), though it's significantly less pleasing on the eyes.
Despite this, it does still offer the touchscreen convenience and slight security benefits while still being able to fit on your keychain.
Two words come to mind when looking at the Ledger Blue: "cool" and "unnecessary". For those crypto ballers out there who don't mind shilling out $269.99 for a hardware wallet with less coin support than it's $99.99 counterpart, we see no reason not to.
That being said, the Blue does function as a very easy-to-use choice that offers more coins than non-ledger competitors.